Note: The job is a remote job and is open to candidates in USA. Helix is transforming healthcare by integrating genomic data into clinical practice through partnerships with health systems and life science companies. The Product Manager will own the end-to-end patient experience for enrolling research participants into Helix’s study platform, leading problem definition, product discovery, validation, roadmap prioritization, and cross-functional delivery in a regulated healthcare environment.
Responsibilities
• Clearly define the customer problem before a single line of code is written — ensuring the team is always solving the right issue
• Maintain a product vision that connects patient and health system needs to Helix's business growth, serving as the primary filter for what is worth building
• Distill complex market signals, partner requirements, and user pain points into narratives that align stakeholders across the organization
• Orchestrate AI tools and agents to synthesize market context, analyze competitive landscapes, and evaluate solution approaches in hours and days rather than weeks
• Direct the idea-to-prototype cycle with urgency, ensuring solutions are user-tested quickly and roadmap pivots are evidence-based
• Own the validation process: analyze stakeholder feedback and behavioral data to make immediate, informed decisions about product direction
• Own and maintain a living roadmap — updated as evidence shifts, not on a quarterly calendar — and make high-stakes tradeoff decisions including what not to build when technical cost is low but cognitive cost to the user is high
• Ensure the health of the Helix Hosted Consent product, including data privacy, security, and governance considerations within a regulated healthcare context
• Collaborate with design, engineering, delivery, research operations, clinical, regulatory, and support teams to ship enhancements that meet user needs and business goals
• Keep the delivery cadence healthy — unblocking the team before blockers become delays, and maintaining quality across the full product lifecycle
• Bridge the gap between AI-driven speed and human alignment — distilling technical outputs into clear narratives that maintain stakeholder trust and drive executive buy-in
• Lead a culture of high-integrity debate: challenge the idea, not the person, and move the team from discussion to conviction quickly
Skills
• 5+ years of product management experience in highly cross-functional and/or customer-centric roles
• Demonstrated AI fluency — you treat AI tools as a core part of your workflow, using them to accelerate discovery, analysis, prototyping, and communication
• Working knowledge of the healthcare industry and regulatory landscape
• You move from ambiguous problem to shipped solution without waiting for someone to hand you a plan — and you do it without losing sight of the user and KPIs
• Excellent communication and interpersonal skills; you know how to say no while making it feel like an opportunity
• Proven track record of successfully managing and improving user experiences for complex digital products
• You build consensus and listen well, but you also drive hard decisions when consensus is not available
• Familiarity with regulated environments, including HIPAA, CLIA/CAP, CCPA/CPRA
• Experience with electronic health records, interoperability, and the US healthcare domain
• Experience working closely with health systems or other enterprise healthcare partners
Benefits
• 10% of your annual salary discretionary annual bonus
• Generous equity at Helix
• Comprehensive Health Insurance with Date of Hire eligibility
• Above average employer paid premium coverage
• 12 weeks Helix Paid Parental Leave option
• 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
• Comprehensive Well-Being Benefits
• Flexible PTO
• Remote options for many roles
• A home office stipend
Company Overview
• We enable health systems, life sciences companies and payers to accelerate the integration of genomic data into patient care and therapeutic development. It was founded in 2015, and is headquartered in San Mateo, California, USA, with a workforce of 51-200 employees. Its website is https://helixworkflo.com.
Company H1B Sponsorship
• Helix has a track record of offering H1B sponsorships, with 3 in 2026, 4 in 2025, 3 in 2024, 3 in 2023, 1 in 2022. Please note that this does not guarantee sponsorship for this specific role.
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